Faculty Profile
Address:
710 West 168th Street
Box 42
New York, NY 10032
Phone: 212-305-0052
gm317@columbia.edu
| Education and Training | ||
| M.D. | 1990 | Yale Univ. School of Med. |
Affiliations
Stem Cell Consortium
Neurological Surgery
| Guy
M. McKhann, M.D. Assistant Professor of Neurosurgery |
Research Summary
Research
Interests
- the role of astrocytes in the development and maintenance of epilepsy
- interactions between astrocytes, neurons, and extracellular space
- brain organization and reorganization of language and sensorimotor function
Selected
Publications
1. Raimondo D'Ambrosio, Jurgen Wenzel1, Philip A.
Schwartzkroin, Guy M. McKhann, and Damir Janigro.
Functional Specialization and Topographic Segregation of Hippocampal
Astrocytes. The Journal of Neuroscience, June 15, 1998,
18(12):4425-4438
2. Guy M. McKhann, Raimondo D'Ambrosio, and Damir Janigro. Heterogeneity of Astrocyte Resting Membrane Potentials and Intercellular Coupling Revealed by Whole-Cell and Gramicidin-Perforated Patch Recordings from Cultured Neocortical and Hippocampal Slice Astrocytes. The Journal of Neuroscience, 17(18):6850-6863
3. Damir Janigro, Sonia Gasparini, Raimondo D'Ambrosio, Guy McKhann, and Dario DiFrancesco. Reduction of K+ Uptake in Glia Prevents Long-Term Depression Maintenance and Causes Epileptiform Activity. The Journal of Neuroscience, 17(8):2813-2824.
4. LK Needham, GI Tennekoon and GM McKhann. Selective growth of rat Schwann cells in neuron- and serum-free primary culture. Journal of Neuroscience, Vol 7, 1-9